Any type of aerobic exercise works for the improvements, study finds.
Exercise is generally good for you, but a new high-quality clinical trial finds that it's so good, it can even knock back colon cancer—and, in fact, rival some chemotherapy treatments.
The finding comes from a phase 3, randomized clinical trial led by researchers in Canada, who studied nearly 900 people who had undergone surgery and chemotherapy for colon cancer. After those treatments, patients were evenly split into groups that either bulked up their regular exercise routines in a three-year program that included coaching and supervision or were simply given health education. The researchers found that the exercise group had a 28 percent lower risk of their colon cancer recurring, new cancers developing, or dying over eight years compared with the health education group.
The benefits of exercise, published in the New England Journal of Medicine, became visible after just one year and increased over time, the researchers found. The rate of people who survived for five years and remained cancer-free was 80.3 percent among the exercise group. That's a 6.4 percentage-point survival boost over the education group, which had a 73.9 percent cancer-free survival rate. The overall survival rate (with or without cancer) during the study's eight-year follow-up was 90.3 percent in the exercise group compared with 83.2 percent in the education group—a 7.1 percentage point difference. Exercise reduced the relative risk of death by 37 percent (41 people died in the exercise group compared with 66 in the education group).
"The magnitude of benefit from exercise... was similar to that of many currently approved standard drug treatments," the researchers noted.
However, the exercise routines that achieved those substantial benefits weren't heavy-duty. Participants were coached to perform any recreational aerobic exercise they enjoyed, including brisk walking. Adding 45- to 60-minute brisk walks three or four times a week, or three or four jogs lasting 25 to 30 minutes, was enough for many of the participants to improve their odds.
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Overall, the goal was to get the exercise group over 20 MET hours per week. METs are Metabolic Equivalents of Task, which represent the amount of energy your body is burning up compared to when you're at rest, sitting quietly. Brisk walking is about four METs, the researchers estimated, and jogging is around 10 METs. To get to 20 MET hours a week, a participant would have to do five hours of brisk walking a week (e.g., five hour-long walks a week) or jog for two hours a week (e.g., four 30-minute jogs per week).
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